This creature sculpt was completed for a sculpting course I took in college. It's based off the beautiful painting by Roby Dwi Antono titled Denyut. The original can be found here.
The entire process from sculpt to render was completed in Zbrush. As I was working form a two-dimensional painting, I began by placing landmark pieces such as the eyeball and the three baby faces (pictured below) and built up the rest of the pieces around them.
Once the sculpting was complete, I chose and applied materials from Pixologic's Matcap Library and painted the sculpt to help match it to the source material.